Spectroscopy
of Biopolymers Syllabus
for 2006 autumn semester
Web:
http://www.cyut.edu.tw/~wjchien Syllabus
Download
Instructor: Wei-Jyun
Chien (錢偉鈞) Applied
Chemistry, CYUT
Tel: 23323000 ext.
7230 or 4307, e-mail:
wjchien@mail.cyut.edu.tw
Lecture: Monday 13:30~14:20; Wednesday
10:10~12:00 (CYUT)
Friday
14:00~17:00 (THU)
Textbooks:
1.
Physical Chemistry 1st
ed.; Thomas Engel and Philip Reid; Pearson Education, Inc.
2.
Instrumental Analysis 4th ed.; Skoog and Leary;
3. Principles of Fluorescence Spectroscopy 2nd ed. J. R. Lakowicz, Kluwer Academic / Plenum Publisher.
1999
4. Circular dichroism : principles and applications 2nd ed. edited by Nina Berova, Koji
Nakanishi, Robert W. Woody. Wiley-VCH , c2000
5.
NMR of Proteins and Nucleic Acids Kurt Wüthrich, Wiley
International Publication. 1986.
6.
Infrared and Raman Spectroscopy, Methods and Applications, edited by Bernhard Schrader, VCH, 1995.
7.
Infrared Spectral Interoretation, A Systematic Approach Brian Smith, CRC Press, 1999.
e-books:
1.
Protein
Structure and Function by Gregory Petsko and Dagmar Ringe, New
Science Press Ltd, 2004. http://www.new-science-press.com/browse/protein
2.
Protein Structure Determination in Solution by Two-Dimensional and
Three-Dimensional Nuclear Magnetic Resonance Spectroscopy Angela M. Gronenborn* and G. Marius Clore* 2Anal. Chem. 1990,
62, 2-15. http://pubs.acs.org/cgi-bin/archive.cgi/ancham/1990/62/i01/pdf/ac00200a003.pdf
Schedule:
|
日 |
一 |
二 |
三 |
四 |
五 |
六 |
Contents |
Slides
|
Text |
Reading Assignments |
|
10 |
11 |
12 |
13 |
14 |
15 |
16 |
Introduction – Resources and tools |
|
|
|
|
17 |
18 |
19 |
20 |
21 |
22 |
23 |
Introduction to Biopolymers I - peptides and
proteins |
|
|
|
|
24 |
25 |
26 |
27 |
28 |
29 |
30 |
Introduction to Biopolymers II – nucleic acids and
hydrocarbons |
|
||
|
10/1 |
2 |
3 |
4 |
5 |
6 |
7 |
Introduction
to Spectroscopy I -Vibrational & Rotational Spectroscopy |
|
||
|
8 |
9 |
10 |
11 |
12 |
13 |
14 |
Applications of IR Spectroscopy on
Biopolymers I |
S3-1 |
|
R1, R2, R3 |
|
15 |
16 |
17 |
18 |
19 |
20 |
21 |
Applications of IR Spectroscopy on
Biopolymers II |
S3-2 |
|
|
|
22 |
23 |
24 |
25 |
26 |
27 |
28 |
Introduction to
Spectroscopy II - Electronic Spectroscopy |
|
||
|
29 |
30 |
31 |
11/1 |
2 |
3 |
4 |
Applications of UV-Vis Spectroscopy
|
|
|
|
|
5 |
6 |
7 |
8 |
9 |
10 |
11 |
Applications
of Fluorescence Spectroscopy on Biopolymers I
|
|
|
|
|
12 |
13 |
14 |
15 |
16 |
17 |
18 |
Applications
of Fluorescence Spectroscopy on Biopolymers II
|
|
|
|
|
19 |
20 |
21 |
22 |
23 |
24 |
25 |
Introduction to
Spectroscopy III – Circular Dichroism Spectroscopy |
|
|
|
|
26 |
27 |
28 |
29 |
30 |
12/1 |
2 |
Applications of CD
Spectroscopy on Biopolymers I |
S5-2
|
|
|
|
3 |
4 |
5 |
6 |
7 |
8 |
9 |
Applications of CD
Spectroscopy on Biopolymers II |
|
|
|
|
10 |
11 |
12 |
13 |
14 |
15 |
16 |
Introduction to
Spectroscopy IV – NMR Spectroscopy |
|
||
|
17 |
18 |
19 |
20 |
21 |
22 |
23 |
NMR Spectroscopy and Protein
Conformational Study |
|
|
|
|
24 |
25 |
26 |
27 |
28 |
29 |
30 |
NMR Spectroscopy and Protein
Conformational Study |
|
|
|
|
31 |
1/1 |
2 |
3 |
4 |
5 |
6 |
Application of NMR techniques on
Biopolymers |
|
|
|
|
7 |
8 |
9 |
10 |
11 |
12 |
13 |
Review
|
|
|
|
|
14 |
15 |
16 |
17 |
18 |
19 |
20 |
Final Exam
|
|
|
|